A multidisciplinary approach to endometriosis management—integrating gynecology, pain management, nutrition, and mental health—can significantly enhance long-term outcomes and quality of life for patients. Endometriosis is a complex, chronic condition that affects not only reproductive health but also daily functioning, emotional well-being, and overall physical health. Gynecologists provide the foundation for diagnosis and medical or surgical treatment, but pain specialists are essential for managing the often-debilitating chronic pelvic pain that can persist even after surgery. Meanwhile, dietitians play a critical role by helping patients adopt anti-inflammatory, hormone-balancing dietary habits that may reduce flare-ups and improve digestion, which is often impacted by endometriosis. Mental health support is equally vital, as many patients experience anxiety, depression, or trauma related to delayed diagnosis, persistent pain, or fertility struggles. By working together, this interdisciplinary team can offer a more holistic and personalized care plan that addresses the physical, emotional, and lifestyle aspects of endometriosis—leading to more sustainable symptom relief and improved overall well-being.