South Korea is at the forefront of stem cell therapy for anti-aging, with cutting-edge advancements in regenerative medicine. One of the most significant breakthroughs is the use of exosome-based stem cell therapy, which enhances skin rejuvenation by promoting cell communication and tissue repair. Additionally, mesenchymal stem cells (MSCs) derived from umbilical cord blood, adipose tissue, and bone marrow are widely used to stimulate collagen production, improve skin elasticity, and reduce wrinkles. 3D bioprinting technology combined with stem cells is also being explored to create personalized skin grafts for anti-aging treatments. Furthermore, gene-edited stem cells are being researched to enhance the longevity and functionality of transplanted cells, leading to longer-lasting and more effective results. Many Korean clinics now integrate AI-driven diagnostics and personalized treatment plans, ensuring that each patient receives customized therapy based on their skin condition and biological aging markers. With strict government regulations and world-class medical facilities, South Korea continues to push the boundaries of stem cell-based anti-aging treatments, attracting patients from around the world.